| Model | Year | Engine power | Displacement | Top speed | 0-100 km/h (0-62 mph) |
|---|---|---|---|---|---|
| Mercedes-Benz R 280 CDI 4Matic | 2006 | 140 kW | 2987 ccm | 210 km/h | 9.8 s |
| Mercedes-Benz R 320 CDI | 2006 | 165 kW | 2987 ccm | 215 km/h | 8.8 s |
| Mercedes-Benz R 350 | 2006 | 201 kW | 3506 ccm | 230 km/h | 8.4 s |
| Mercedes-Benz R 500 | 2006 | 226 kW | 4966 ccm | 245 km/h | 7 s |
| Mercedes-Benz R 63 AMG 4Matic | 2006 | 376 kW | 6208 ccm | 250 km/h | 5.1 s |
| Mercedes-Benz S 320 CDI | 2006 | 173 kW | 2987 ccm | 250 km/h | 7.5 s |
| Mercedes-Benz S 350 | 2006 | 201 kW | 3497 ccm | 250 km/h | 7.3 s |
| Mercedes-Benz S 350 L | 2006 | 201 kW | 3498 ccm | 250 km/h | 7.3 s |
| Mercedes-Benz S 350 Sedan | 2006 | 180 kW | 3720 ccm | - | - |
| Mercedes-Benz S 430 Sedan | 2006 | 206 kW | 4261 ccm | - | - |
| Mercedes-Benz S 500 | 2006 | 286 kW | 5461 ccm | 250 km/h | 5.4 s |
| Mercedes-Benz S 500 L | 2006 | 286 kW | 5461 ccm | 250 km/h | 5.4 s |
| Mercedes-Benz S 500 Sedan | 2006 | 226 kW | 4965 ccm | - | - |
| Mercedes-Benz S 500L B4 SGuard Automatic | 2006 | 226 kW | 4966 ccm | - | - |
| Mercedes-Benz S 55 AMG Sedan | 2006 | 368 kW | 5441 ccm | - | - |
| Mercedes-Benz S 600 | 2006 | 381 kW | 5513 ccm | - | 4.6 s |
| Mercedes-Benz S 600 Bi-T Sedan | 2006 | 368 kW | 5506 ccm | - | 4.9 s |
| Mercedes-Benz S 65 AMG Sedan | 2006 | 451 kW | 5982 ccm | - | 4.2 s |
| Mercedes-Benz S V12 Biturbo | 2006 | 451 kW | 6233 ccm | 340 km/h | - |
| Mercedes-Benz SL 350 | 2006 | 201 kW | 3498 ccm | 250 km/h | 6.6 s |
